Abnormal Visual System Connectivity in Human Albinism
نویسندگان
چکیده
منابع مشابه
Perceptual relevance of abnormal visual field representations: static visual field perimetry in human albinism.
BACKGROUND In human albinism the plasticity of the visual system is challenged, as part of the temporal retina projects abnormally to the contralateral hemisphere. AIM To investigate whether the sensitivity of the abnormally projecting temporal retina is preserved. METHODS Light spot detection sensitivities were assessed in the central 20 degrees of the visual field in 15 patients with albi...
متن کاملMeasuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography.
In albinism, the number of ipsilaterally projecting retinal ganglion cells (RGCs) is significantly reduced. The retina and optic chiasm have been proposed as candidate sites for misrouting. Since a correlation between the number of lateral geniculate nucleus (LGN) relay neurons and LGN size has been shown, and based on previously reported reductions in LGN volumes in human albinism, we suggest ...
متن کاملAbnormal lateral geniculate nucleus and optic chiasm in human albinism.
Our objective was to measure how the misrouting of retinal ganglion cell (RGC) fibers affects the organization of the optic chiasm and lateral geniculate nuclei (LGN) in human albinism. We compared the chiasmal structures and the LGN in both pigmented controls and patients with albinism by using high-resolution structural magnetic resonance imaging (MRI). We studied 12 patients with oculocutane...
متن کاملOrganization of the visual cortex in human albinism.
In albinism there is an abnormal projection of part of the temporal retina to the visual cortex contralateral to the eye. This projection, together with the normally routed fibers from nasal retina, provides a cortical hemisphere with visual input from more than the normal hemifield of visual space. In many mammalian models of albinism, a possible sensory mismatch in the visual cortex is avoide...
متن کامل[Albinism: diagnosis by visual evoked potentials].
BACKGROUND In albinism the majority of the nerve fibers of the optic nerve originating from an eye are innervating the contralateral hemisphere. As a result of the predominantly monocular innervation of the left and right hemispheres, the unilateral activation of the visual cortex (lateralization) can be detected with visual evoked potentials (VEP). PATIENTS AND METHODS The VEPs were elicited...
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ژورنال
عنوان ژورنال: Journal of Vision
سال: 2016
ISSN: 1534-7362
DOI: 10.1167/16.12.772